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chronic kidney disease

Treatment Guidelines for Diabetic Nephropathy

Diabetic nephropathy characterizes a huge chunk of any nephrologist’s practice. Some of the issues to tackle with each visit are obvious–e.g., adequate glucose control, minimization of proteinuria, control of blood pressure–and generally much easier to talk about than…

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CKD in the Elderly

A current controversy in the CKD community involves definitions of CKD in the elderly. The issue is not trivial: were we to apply the standard KDOQI definitions of CKD staging, using the MDRD equation to estimate GFR, this…

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TGF-betas & diabetic nephropathy

The TGF-beta family of proteins has wide effects on nearly every tissue of the body–it is one of the key players in a mammalian development and homeostasis.  It also has particular relevance to renal pathophysiology as one of…

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