Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Urine Sediment of the Month: The Thin Waxy Cast
The thickness of the fluid layer examined by urinary microscopy is determined by the volume of resuspended sediment put on the glass slide and the size of the coverslip. Using 13-15ul of sediment and coverslips of 18x18mm2 as…
The Case of the Missing Casts
A 50 y/o woman presents with symptoms of fatigue and malaise for 1-2 weeks. Medications include ACE, HCTZ, and a multivitamin daily. She had a UTI 6 weeks ago that did not improve after a 5 day course…
Urine Sediment of the Month: Oblique Illumination in Microscopy
Urinary sediment microscopy is a diagnostic technique designed to acquire 2-dimensional images of structures present in a slide. However, 2-dimensional views may lack sufficient contrast to allow for optimal visualization. One way to enhance the images and create…
Urine Sediment of the Month: Identifying Phagocytosed Particles
“What am I looking at? ” Phagocytosis and particle internalization by cells in the urine is not common, but of clinical interest when it occurs.Phagocytosis/particle internalization can be observed in urine microscopy by the usual culprits: professional phagocytes…
Urine Sediment of the Month: Beyond the Urizon
One of the welcome side-effects of doing your own urine sediment examination is having easy access to a microscope and some basic lab equipment. This allows you to examine all sorts of things besides urine (Fig. 1). For…
Urine Sediment of the Month: To Stain or Not to Stain
To stain, or not to stain, that is the question. Different illumination techniques are available to visualize the formed elements in the urinary sediment. The two most commonly used are brightfield and phase contrast. Brightfield illumination provides high…
Urine Sediment of the Month: Pathologic Crystals in the Urine
Urinary crystals are a frequent finding and there are several different types that can be observed under the microscope. We’ve discussed some of these crystals in a previous Urine Sediment of the Month post. Unlike these more common…
Urine Sediment of the Month: Crystal Casts
Identification of crystals and casts by microscopic examination of the urinary sediment is of clinical importance. Specifics about crystals and casts have been previously covered in preceding posts of this blog. Interestingly, crystalline structures can occasionally be embedded…
Urine Sediment of the Month: Urine’s True Colors
The golden days of urine are here to stay, and “liquid biopsy” is not just for NephMadness. Discolorations of urine are common and never fail to startle both patients and professionals. When analyzing urine coloration, it is helpful…
Urine Sediment of the Month: Mixed Cellular Casts
As we have covered before, RBC casts most often signify the presence of glomerulonephritis while WBC casts are indicative of an inflammatory process affecting the glomeruli or interstitium. Sometimes, casts can be seen which contain both red and…