The collapsing form of FSGS is a histologic variant which is characterized by mesangial hypercellularity and resultant collapse of the glomerular capillaries, as illustrated in the photo to the left. Its identification is important for prognostic reasons as…
Nephrotic Syndrome Trivia Question: Name two different athletes, both with nephrotic syndrome due to focal segmental glomerulosclerosis (FSGS).Answer: Most people are aware of Alonzo Mourning, the NBA center who was diagnosed with FSGS which forced his temporary retirement…
There are many diseases which can recur following renal transplant: examples include IgA Nephropathy (which has a very high rate of recurrence on follow biopsy but is rarely clinically relevant in that it does not cause significant allograft…
We all know that FSGS can exist in both primary and secondary forms. In both cases light microscopy identifies partially (“segmental”) sclerotic glomeruli in a variable (“focal”) distribution in the biopsy. How can you tell the different between…
