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Nathan Hellman

Nail-Patella Syndrome

Too long have I seen the “Nail-Patella Syndrome” included in the differential diagnosis of renal disease without understanding anything about it…that ends today! The Nail Patella Syndrome (NPS), also referred to as Hereditary Onychoosteodysplasia, is an autosomal dominant…

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Death by Soy Sauce?

Bizarre case of hypernatremia:  a suicide attempt by a 73 year-old Japanese man in which the individual drank massive amounts of soy sauce.  According to this 2006 Neurology paper by Machino et al, the patient presented with vomiting,…

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Aquaporins and the Kidney

The discovery of aquaporins–the protein family of water channels which regulate water transport in the kidney and many other tissues–was considered significant enough to win the Nobel Prize in Chemistry for Peter Agre in 2003.   The aquaporins…

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