Renal Physiology PenCasts

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Improving preclinical nephrology education during medical school is a hot topic in nephrology these days. John Roberts, a nephrology fellow at Duke, recently produced a collection of short (10-15min) videos on renal physiology in an effort to do just this. These videos are geared towards 1st year medical students and are meant to compliment other learning styles such as book reading, group learning or standard didactic lectures. Take a look at the videos and offer any comments or suggestions. These are fantastic videos that really break down the essence of basic renal physiology that is the foundation of our field. Kudos to John for taking on this project. They look great! Mike Berkoben of Duke Nephrology makes an appearance as well.

Tubular Transport 1 
Tubular Transport 2
Regulation of Body Fluid Osm 1 
Regulation of Body Fluid Osm 2 
Body Fluid Compartments: Regulation of ECFV 1 
Body Fluid Compartments: Regulation of ECFV 2 
Potassium 1
Potassium 2
Acid Base Physiology 1 
Acid Base Physiology 2 
Acid Base Physiology 3

Link to all of the videos


  1. John,

    I would like to talk to you about an idea you might be interested in.

    I could not find your email in the Duke website so I was hoping you can email me to:


  2. Thanks for the feedback Dr. Rondon. The effect of ADH on solute transport does not get as much attention as the effect on water transport. I also struggle with how much detail to give MS1's regarding concentration and dilution. Some suggest not even mentioning counter-current multiplication.

  3. Nice videos. I was looking at the 2nd video of regulation of body fluids osm and noticed that you showed that in the absence of ADH the corticopapillary gradient still reaches 1200 mOsm/L at the tip of the papilla. This is not the case. ADH also works by increasing solute delivery into the medulla by increasing activity of NKCC2 in TAL (increasing NaCl delivery) and UTA1 in IMCD (increasing urea delivery). Therefore, in the absence of ADH, the medullary gradient does not reach more than 600 mOsm/L at the tip of the papilla.

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