The electrolyte bracket contains a mixture of the old staples of nephrology mixed with some new kids on the block trying to muscle in on established territory, Vaptans vs hypertonic saline and ZS-9 vs Kayexalate. Hypertonic saline is…
In the kidney stone bracket I think the most disappointed team must be XO inhibitors. Allopurinol has been around for a long time and is one of the mainstays of treatment for gout. More recently, febuxostat hit the…
In the Renal Replacement bracket we see all the usual players, except for convective clearance, which is not in mainstream use in chronic dialysis units in the US. It is relatively unknown this side of the Atlantic (west…
In the AKI bracket one team caught my eye, RIPC, Remote Ischemic Preconditioning. This is a procedure of inducing transient ischemia in the arm by inflating a BP cuff for 5 minutes x2 with an interim deflation for…
The kidney regeneration bracket is full of heavy weights as usual! However, not being in the field myself one team jumped out for me, Bioartificial Kidney. As the authors of this piece say this is truly the holy…
In the poisons and toxins bracket I learnt some interesting facts. The Dietary Supplement Health and Education Act of 1994 (DSHEA 94) is an example of the power of big business in Washington. Subsequent to acts such as…
So it is that time of the year again, NephMadness 2014! I am hoping it doesn’t distract me too much from the basketball… This year’s bracket has thrown up some very interesting match ups. I had a really…
This is my contribution to the Dream RCT in Nephrology poll being coordinated by UKidney. As a nephrologist it seems one spends a lot of time trying to rationalize the use of diuretics in the Cardio-Thoracic ICU. Volume…
Genome-wide association studies (GWAS) are large population based collaborative studies seeking genetic patterns that would explain common complex phenotypes. These large studies have given us much insight into the genetic risk profile of patients with diseases such as…
