Browsing tag

anti-HLA antibody

Donor specific antibodies made easy

May 16, 2018

Donor specific Antibodies (DSA) are one of the established biomarkers for predicting antibody mediated rejection (ABMR). This blog is a short synopsis on DSA and their complex characteristics in kidney transplantation. DSA may be preformed (before transplantation) or de-novo…

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Is Matching at the HLA Epitope Level the Holy Grail of Longer Graft Survival?

March 5, 2015

All HLA antigens are composed of strings of several polymorphic sites, which may serve as targets, or epitopes, for antibody binding. An important consideration is that HLA antigens have multiple epitopes that can be recognized by specific antibodies….

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