Midodrine in Hemodialysis: Could it do More Harm than Good?
Midodrine [1-(2′,5′- dimethoxy phenyl-1)-2- glycinado-ethanol (1)- hydrochloride] is a prodrug with rapid and near complete bioavailability after oral administration resulting in peak plasma levels 40 minutes after oral consumption. Midodrine is then converted by enzymatic cleavage in the…