IgA nephropathy (IgAN) is the most common form of glomerulonephritis worldwide, and is responsible for ~10% of glomerulonephritis in the United States. IgA nephropathy can be primary or secondary. The pathophysiology of primary IgAN is complex and incompletely…
In an ideal world, patients would present to our clinic with straightforward conditions, allowing us to confidently treat the patient with effective medications which will likely have much more benefit than harm. However, we also commonly encounter patients…
Despite being the world’s most common form of glomerulonephritis, IgA Nephropathy treatment strategies have hereto been controversial, particularly surrounding the use of immnosuppression on top of traditional RAAS blockade. The long awaited, Intensive Supportive Care plus Immunosuppression in…
At this year’s ASN Kidney Week in Philadelphia Andrey Shaw, MD, presented the inaugural Michelle P Winn Endowed Lectureship. Dr Shaw was not only a longtime collaborator of Michelle’s but also a very close personal friend making him…
Following on from yesterday’s update on membranous nephropathy, I thought that this would be a good time to give an update on the treatment of another, very common glomerular disease: IgA nephropathy. IgA has been covered extensively on…
A man in his 30s with no significant medical history presented to the ED following a fainting episode. Routine screening found an abnormal creatinine, hematuria and proteinuria. Serological work-up including complements were negative. In view of a slowly…
The topic of IgA nephropathy has been discussed in multiple posts here in the past. IgA is the commonest primary GN with a wide variety of presentations and prognoses ranging from isolated hematuria to a rapidly progressive GN….
To many of us IgA nephropathy (IgAN) is a disease to be watched and monitored. Most cases of IgAN in which the clinical course is aggressive occur with one of two atypical presentations: 1. Acute kidney injury (AKI)…
The NKF Spring Clinical meeting started today in Las Vegas. I thought I’d share of the interesting highlights from some of the talks I’ve attended. This post relates to Dr Appel’s lecture on IgA nephropathy, where he described…
IgA nephropathy is the most common cause of glomerulonephritis in countries where renal biopsies are commonly performed. See a previous post on the wide variety of presentations with this syndrome and this review. But what do we know…
