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Michael Lattanzio

ARBs and Cancer Risk?

In the summer of 2010, I came across a health report on the national news that was titled “Angiotensin Receptor Blockers Linked to Cancer”.  The headline was based on a publication that demonstrated an increased cancer signal associated…

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Board question: Transplant answer

The correct answer is D. The criteria for expanded-criteria donors (ECD) are: age greater than 60 years old OR age 50 to 59 years old and at least two of the following: History of hypertension Terminal creatinine >…

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Board question: Water-1 answer

This was an actual case I saw and thought it generated a multitude of interesting dilemmas. When I initially examined the patient she was in status epilepticus. This, by itself, mandated the immediate correction of her serum sodium….

Board question of the week: Water-1

A 40-year-old woman is rushed to ER for change in mental status. She has a history of multiple sclerosis and alcohol abuse. On arrival to ER, she exhibits 3 stereotyped, tonic-clonic seizure that resolve with ativan. The initial…

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Board Review; Pregnancy answer

Each of the following choices is expected to occur during pregnancy except for A and D. Let’s go through each of the possible choices. A. This in partially incorrect. Hyperventilation (with resultant hypocapnea, not hypercapnea) occurs during pregnancy…

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Board question of the week: PD-1

A 55-year-old woman with ESRD secondary to lupus nephritis presents to the PD clinic with volume overload. She reports decreased UF volume, despite the use of 4.25% dextrose exchanges over the last few weeks. She has been on…

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Board question: Transplant-1 answer

The vast majority of people answered correctly; the best answer is D. Approximately 3-5% of patients with Alport’s syndrome develop de novo anti-glomerular basement membrane (GBM) disease in the transplanted kidney. Alport’s syndrome is a genetic disorder that…

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Board question: Hypertension-1 answer

The best answer is D. Lifton et al. described a single gene mutation on the hormone-binding domain of the mineralocorticoid receptor (MCR). Individuals with this missense mutation develop early-onset hypertension with characteristic low renin and aldosterone levels. The…

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