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tacrolimus

The ELITE & the Rest in Kidney Transplantation

The ELITE-Symphony study enshrined standard triple therapy immunosuppression of tacrolimus, mycophenolic acid and prednisolone, for renal transplant recipients. We get familiar with these agents relatively quickly in our renal training, but what about the other less common agents…

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Tacrolimus Formulations

Tacrolimus comes in oral, intravenous and topical formulations. Prograf is the most commonly used oral tacrolimus formulation and is dosed twice daily. Prograf pharmacokinetics  Absorption: Absorption occurs in the small intestine. Drug levels reach a maximum concentration in…

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