Dialysis in Neonates
Recently, there was an article in Slate magazine that detailed the very difficult decision that had to be made by a pregnant woman who discovered at 18 weeks gestation that her baby had complete bladder outlet obstruction with…
Treatment of secondary amyloid
Recently I’ve been dealing with an unfortunate individual with a long history of RA who has developed nephrotic range proteinuria after being stable for many years. Despite the deteriorating renal function, NSAIDs have been continued because without them…
Screening for CKD – The new ACP guidelines – Part 3
Recommendation 3: The ACP recommends that clinicians select pharmacologic therapy that includes either an angiotensin-converting enzyme inhibitor (moderate-quality evidence) or an angiotensin II-receptor blocker (high-quality evidence) in patients with hypertension and stage 1 to 3 chronic kidney disease….
Screening for CKD – The new ACP guidelines – Part 2
Recommendation 2: The ACP recommends against testing for proteinuria in adults with or without diabetes who are currently taking an angiotensin-converting enzyme inhibitor or an angiotensin II-receptor blocker. (Grade: weak recommendation, low quality evidence) This is an interesting…
Screening for CKD – The new ACP guidelines – Part 1
A few days ago, I was asked to present the new ACP guidelines for screening for CKD stages 1-3 to a group of non-nephrologists. These guidelines were published online last October in Annals of Internal Medicine and provoked…
Top 10 Nephrology 2013 – Summaries
Four days left to vote for the top nephrology story of 2013. So far, the top 3 are: The CORAL Trial The Nephron-D Trial JASN paper showing improved mortality for online HDF compared with standard HD. The first…
KIM1 and Kidney Disease: Contender for Top 10 of 2013
Although I don’t believe that many will agree that this was the most important paper of the year in the world of nephrology, I do want to give a shout out to a paper published in JCI in…
Ultrasound and Nephrologists
Registration has opened for the Spring session of the Ultrasound course for Nephrologists at Emory University. It will be held on Feb 1-2 2014, in Atlanta. The brochure for the upcoming course is available here.
Tolvaptan and the FDA – A patient’s perspective
Over at the Atlantic this week, an article was published written by one of the people who took part in the early trials of tolvaptan for APKD. The article shows just how much hope people with this disorder…
Type B Lactic Acidosis
Nice case report in AJKD recently raised the issue of Type B Lactic Acidosis. Lactic acidosis occurs when there is excessive anaerobic glycolysis or decreased removal of lactate from the circulation. Classically, Type A lactic acidosis is related…