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Water deprived

Recently in the clinic we were asked to review a patient with suspected diabetes inspidus. She had been taking lithium for more than 20 years for bipolar disorder that was very well controlled. During a routine medical examination,…

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How to manage lithium toxicity

I recently saw a patient in the emergency department with chronic lithium toxicity and took the opportunity to do some review. Three broad patterns of lithium toxicity are recognized: Acute toxicity – Seen in patients not previously taking…

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Lithium-induced nephrotoxicity

I recently saw a patient in my outpatient clinic who was referred for management of chronic kidney disease presumed to be caused by chronic lithium-induced nephrotoxicity. The patient presented with a serum creatinine ranging from 1.4-1.5 mg/dL over…

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