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Confusing Sign

Everyone has a certain diagnosis in Nephrology that is just hard to understand. For me, it has been the diagnosis of MPGN (membranoproliferative glomerulonephritis). After extensive reading, I have developed a couple of pearls and interesting points that…

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Classification of Cryoglobulins and MPGN

Cryoglobulinemia is characterized by the presence of circulating antibodies which precipitate at cooler temperatures, and not infrequently leads to renal failure/glomerulonephritis. The stereotypical histologic lesion of cryoglobulinemia is membranoproliferative glomerulonephritis, which takes the appearance on light microscopy of…

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