What’s a picture of Mozart doing on the Renal Fellow Network? Fellow renal fellow Lisa Cohen gave a presentation on nephrotic syndrome at our Renal Grand Rounds and discussed evidence that Mozart, who died at the young age…
Identifying the “permeability factor” for patients with FSGS or minimal change disease has been one of the “holy grails” of nephrology, and our inability to identify such a factor has not been for any lack of trying. One…
I went to a very memorable talk today at our Renal Grand Rounds during which fairly convincing data was presented that identifies the long-sought-after antigen which causes membranous nephropathy–still the most common cause of adult-onset nephrotic syndrome in…
Cyclosporin A (CsA) has been a mainstay of therapy for nephrologists: it (along with tacrolimus) has become the cornerstone of immunosuppressant therapy for kidney transplant patients; in addition, it has also seen use as an effective agent in…
Congenital nephrotic syndrome only makes up between 2-8% of all forms of nephrotic syndrome, but is a hot topic in that there are numerous genes continuously being identified which are helping to advance our understanding of podocyte biology….
Any nephrologist practicing in the U.S. does not need to be told that there is an increased incidence of end-stage renal disease in blacks. Furthermore, certain diseases–such as collapsing focal segmental glomerulosclerosis (FSGS), occur almost exclusively in black…
The zebrafish kidney is being increasingly studied, as it appears to offer several advantages for studying renal function. For one, it is transparent, allowing one to visualize kidney development in real-time. Second, it is a simplified system consisting…
The collapsing form of FSGS is a histologic variant which is characterized by mesangial hypercellularity and resultant collapse of the glomerular capillaries, as illustrated in the photo to the left. Its identification is important for prognostic reasons as…
Nephrotic Syndrome Trivia Question: Name two different athletes, both with nephrotic syndrome due to focal segmental glomerulosclerosis (FSGS).Answer: Most people are aware of Alonzo Mourning, the NBA center who was diagnosed with FSGS which forced his temporary retirement…
