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Urea and Hyponatremia

Urea is a hyponatremia treatment long forgotten in the United States. Chronic SIADH is usually managed either by vaptans or a combination of fluid restriction, salt and furosemide. However, vaptans are very expensive and few patients can afford…

Appropriate or inappropriate: stop guessing

In the evaluation of patients with hyponatremia (serum Na less than 135 mEq/L), differentiating hypovolemia from euvolemia is often challenging, particularly if the history and physical findings are unrevealing and frequently leads to misdiagnosis. This conundrum exists even…

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Ecstasy-Induced Hyponatremia

The recreational drug ecstasy (MDMA) is known to result in hyponatremia–which has been reported to result in seizures and death–has a multifactorial mechanism which is interesting. MDMA is associated with elevated ADH levels. In addition, individuals who take…

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