“The best way to predict your future is to create it“. Abraham Lincoln Predicting the future is a tenuous concept and at face value is perhaps better suited to popular media and science fiction than medicine. We have…
Raji* was feeling increasingly distraught as she waited at the doctor’s clinic with her 14 yr old daughter. The teenager had not been eating well and was losing weight for the past 6 months. She was always tired…
Stanifer et al. JASN May 15, 2017 After a series of trials which included individuals receiving dialysis, the benefit of statin-based therapies as eGFR declines, particularly to the point of requiring renal-replacement therapy, has been uncertain (link, link)….
What would you do if you had chronic pain and a GFR of 90? Would you think twice about a two-month (or longer) course of NSAIDs? What if your GFR was 60? Or 30? As society grows increasingly…
PPIs have been associated with AKI including acute interstitial nephritis; CKD development; and CKD progression to ESRD. That is, in over 10,000 Atherosclerosis Risk in Communities participants followed for at least 10 years, incident CKD developed among PPI…
How important is obesity to the field of nephrology? Perhaps obesity is the single strongest risk factor for CKD in the US and most of the developed world. While genetics are certainly important, obesity drives the diabetes epidemic…
Proton pump inhibitors (PPIs) are one of the most commonly prescribed medications, mostly because of their efficacy and their favorable safety profile. However, it has been estimated that between 25% and 70% of these prescriptions do not have…
Metformin is one of the most useful drugs in patients with type 2 diabetes and yet its use in patients with CKD is limited by the perceived association with lactic acidosis. These concerns are due to the association…
Hypertension in diabetic patients increases the risk of microvascular and macrovascular complications. It is quantitatively and qualitatively different from the non-diabetic population and characterized by disturbed circadian rhythm of blood pressure (BP) with increased variability. It also features…
There was a fascinating case published a couple of months ago in the American Journal of Medicine. I have a particular interest in this case as it was my clinic mentor, Julian Seifter, who made the diagnosis and…
