Clayton BradyMD/PhD Candidate (G2)University at Buffalo Jacobs School of Medicine and Biomedical Sciences Acid-base balance is often overlooked in healthy individuals, but becomes glaringly important in any patient with reduced kidney function. Our kidneys do a tremendous job…
Justine Abais-Battad, PhDInstructor, Medical College of Georgia at Augusta University Over the last decade we have witnessed surging scientific and public interest in the gut microbiota and its relationship to our overall health. German philosopher Ludwig Feuerbach said…
Oxalate is a terminal metabolite in humans. Glyoxylate becomes glycine and pyruvate via alanine-glyoxylate aminotransferase (AGT) action, and excess glyoxylate gets converted to oxalate by lactate dehydrogenase (LDH) and glycolate oxidase. Besides being derived endogenously through metabolism, oxalate…
As an avid spicy-food eater, I quickly learned the many home-remedies to help with the dreaded heartburn that often accompanies my jalapenos and hot wings. My secret? Well, without fail, a spoonful of Arm & Hammer baking soda…
Understanding chronic kidney disease (CKD), and its associated health risks, has been a priority for clinical and basic researchers alike. For years, the role of serum uric acid levels in CKD as a marker or causal factor have…
I always like to remind my cardiology colleagues that some of the most important drugs used in the cardiovascular arsenal, are in fact exerting their benefits through the kidneys. Case is point, drugs that target the renin-angiotensin-aldosterone system….
It is not often you see components of a basic metabolic panel (BMP) as a headline in the news. However, in one corner of the world, “creatinine” has become a term that commonly used by the public. It…
Doing my nephrology training in San Francisco, CA has made it clear to me that homelessness is an essential health policy issue. 553,742 people experience homelessness in the United States as of January 2017. While San Francisco has…
APOL1 is the newest addition to the list of CKD risk factors- possibly never before in the history of nephrology has a gene associated with such a high odds ratio with disease – above 7 for hypertensive…
Recently the FDA approved one of the newer exchange resins (Lokelma, ZS-9) for the treatment of hyperkalemia. (Veltassa, Patiromer), a calcium based cation exchange resin, was recently developed and approved since 2015 for the treatment of hyperkalemia. These…
