The debate about which thiazide diuretic to prescribe patients with hypertension has been going on for years without resolution and both HCTZ and chlorthalidone have their supporters. This topic has been discussed in the past on the blog…
Cystinosis is an autosomal recessive disease caused by a mutation in CTNS, which encodes the lysosomal transporter of cystine. This leads to intracellular cystine accumulation which leads to renal, neurological and cardiac damage. The treatment for this condition…
A woman in her early 30s presented to the renal clinic with sudden onset edema. Her urinalysis revealed 4+ protein and 3+ blood. Dysmorphic red cells were noted on microscopy. Apart from her edema, she had no other…
Every year we like to publicize the MDIBL origins of renal physiology course. This is a great opportunity for renal fellows and the fact that it is free apart from transportation costs is a huge bonus. This is…
One of the issues surrounding the study of bardoxolone in animal models was that, because of the way that it is metabolized in rats and mice, it is highly toxic when given for long periods. This specific toxicity…
These are my brackets for the eAJKD nephmadness. My winner is a number 10 seed coming out of left field. For me, the importance of the MDRD trial is that it highlighted the high prevalence of CKD in…
An elderly woman presented for evaluation to the rheumatology service with arthritis and neuropathy. She was hypertensive and had microscopic hematuria with dysmorphic red cells on microscopy. Her creatinine was 1.6 which had not changed in the previous…
The ASN has out together this video announcing a new initiative to attract trainees to nephrology early in their careers. This would involve sponsoring medical students to attend the week-long origins of renal physiology course in Bar Harbor,…
It’s an important anniversary for the Brigham and Women’s Hospital and as a result there are events planned in all departments of the hospital over the next year. Not to be left out, the Renal Division invited some…
The American Journal of Kidney Diseases published a fascinating letter this month from Jochen Reiser’s group concerning the transmission of the suPAR from a mother to her newborn infant. The patient in question had a history of primary…
