The lack of transplantable kidneys is an unavoidable problem for those of us who practice Nephrology. Whilst government policies and extended criteria for donor organs have a role to play in solving this problem, it has always seemed…
To many of us IgA nephropathy (IgAN) is a disease to be watched and monitored. Most cases of IgAN in which the clinical course is aggressive occur with one of two atypical presentations: 1. Acute kidney injury (AKI)…
The UK Renal Association (RA); the professional body for UK nephrologists and renal scientists, has recently started a website to foster discussion of interesting cases (There is also a link in the sidebar). The site remains embryonic whilst…
One of the most important concepts in nephrology is that of chronic systemic inflammation and its role in increased cardiovascular (CV) risk in patients with chronic kidney disease (CKD) and those on dialysis. Despite a significant research effort…
The use of the protocol transplant biopsy is a divisive topic: some units see a protocol program as necessary for proper management post-transplantation, whilst others deride the whole concept as unnecessary. So who is right? Protocol biopsies are…
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The maintenance of mean arterial pressure to prevent tissue dysoxia and conserve organ function is central to the management of the critically ill. In patients with increased capillary permeability this is often achieved by administration of large volumes…
KDIGO (page S6 of PDF) and the UK renal association have recently published guidelines for the clinical care of kidney transplant recipients. Both of these documents suggest that recipients at ‘higher immunological risk’ should be considered for induction…
