A 20-year-old female had Henoch-Schönlein purpura since age 9 leading to ESRD. She underwent kidney transplantation in 2018 from a live donor (mother) and received induction immunosuppression with thymoglobulin (100 mg once) followed by maintenance with tacrolimus (6…
This week Brazil’s capital, Brasília, hosts the World Water Forum, with more than 8,000 participants. Representatives from 172 countries, including political leaders, UNESCO and United Nations members. The theme concerns nature-based solutions to improve fresh water quality and…
CMV infection still remains one of the most common and unpredictable complications in transplant recipients, and the negative consequences in terms of graft lost and recipient survival are well known. In this setting, I would like to present…
Nice debate on ASN Transplant Community about the use of IVIG for BK nephropathy. Personally, I have used IVIG in a handful of patients with refractory BK nephropathy in the past. However, I have convinced myself that there…
A short article was recently written on Washington Post by a medical student who donated a kidney at age 18 to his brother’s stepfather and now regrets it. Worth a reading (link here). He questioned the informed consent…
Patient is a 37-year-old female with cystic fibrosis, recurrent nephrolithiasis who presents to clinic with asymptomatic bilateral kidney stones (8mm on right; 2mm on left) on imaging. What type of stone and why cystic fibrosis (CF) is associated…
The recently published paper in the NEJM entitled “Survival Benefit with Kidney Transplants from HLA-Incompatible LiveDonors” caused a huge impact on Brazil’s media. Our main broadcast TV devoted few minutes explaining it, suggesting as a real breakthrough. Patients…
I was quite excited to see the development of novel agents to help us manage hyperkalemia in our kidney patients in place of kayexalate, which is extremely unpleasant for patients, is associated with diarrhea and have reported severe…
For my inaugural RFN post, a special case I saw last year with Dr. David Mount and Young-Soo Song a fellow nephrologist in training at BMC. A 74-year-old man with history of HTN, peripheral artery disease, CKD (baseline…
Renal transplantation reduces mortality in elderly patients by more than 50%, however, challenges are magnified in elderly renal transplant recipients (RTR) when managing their pharmacotherapy regimen. Aging is associated with changes in several pharmacokinetics parameters including absorption, distribution, metabolism,…
