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transplant infectious diseases

Parvovirus B19 and the Kidney

Parvovirus B19 (PVB19) is a small, non-enveloped, single-stranded DNA virus belonging to the Erythrovirus genus, named for their tropism for erythroid precursor cells. It is the only known parvovirus to infect humans. By late adulthood, most people have…

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The use of IVIg in Kidney Disease

It’s time for a quick nephro-centric summary of immune globulin use. Immune globulin, usually administered intravenously (IVIg), is made from pooled human plasma and used for a wide variety of human disease. It contains mostly IgG with various…

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Hepatitis B and kidney transplantation

Prior HBV infection is not a contraindication to kidney transplantation.  It is critical to evaluate patients with serologies and HBV DNA viral load prior to transplant. Most patients should also undergo liver transplant biopsy to exclude significant fibrosis/cirrhosis. Patients with…

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Does JC Virus Nephropathy Exist?

The JC virus is a member of the Polyomavirus family, which includes the BK virus.  It infects about 80% of healthy adults and establishes latency in renal tissue. It was first isolated in 1971 from the brain of…

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Management of CMV after transplantation

Pre-transplant: All the donors and recipients of kidney transplants (both living and deceased) should be tested for status of CMV by CMV IgG in the blood. If there is history of recent transfusion, pre-transfusion status should be regarded…

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