Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Glucocorticoid-Remediable Aldosteronism
Glucocorticoid-Remediable Aldosteronism (GRA) is an inherited autosomal dominant disorder which causes early-onset (often childhood) high blood pressure, often occuring in individuals with Celtic ancestry. It typically presents with standard symptoms of aldosteronism (hypertension, hypokalemia, and metabolic alkalosis) with…
How To Measure Renal Plasma Flow (RPF)
Question: How is renal plasma flow (RPF) measured? Answer: By measuring para-aminohippurate (PAH) clearance. How does it work? Ideally, one would simply choose a substance which is neither synthesized nor metabolized by the kidney; the amount of such…
Aliskiren
Are renin inhibitors the next big weapon in the fight against hypertension? As we all know, ACE-I’s & ARB’s have so many renoprotective effects that there is substantial evidence towards using these medications as first-line agents for blood…
Hereditary Magnesium Wasting
There are a variety of interesting genetic diseases that can cause hereditary Magnesium wasting. Renal magnesium handling is a little different than other ions in that the primary site of reabsorption is not the proximal convoluted tubule. Rather,…
FGF23
For many years, the existence of “phosphatonins”–substances secreted by certain tumors which result in profound renal phosphorus wasting and resultant osteomalacia–has been postulated. Evidence has recently been accumulating that fibroblast growth factor 23 (FGF-23) is the phosphatonin we…
Renal Aspects To Hepatic Encephalopathy
I was consulted yesterday on a patient with liver and renal failure–obviously, not an uncommon occurrence, as the two often go hand in hand. The patient had presented with altered mental status, and the question came up: hepatic…
Foscarnet & Hypocalcemia
A quick fact about foscarnet, one of the many drugs which can cause drug-induced hypocalcemia. Foscarnet is an antiviral medication, commonly used in the treatment of herpesviruses and CMV infections (e.g., CMV retinitis). The mechanism of its hypocalcemic…
Ultrasound Criteria for ADPKD
Autosomal dominant polycystic kidney disease (ADPKD) acconts for about 10% of patients on dialysis in the U.S. and occurs in 1:400 – 1:2000 live births. As the disease is inherited in an autosomal dominant fashion, the question of…
Welcome to the Renal Fellow Network
Welcome to the Renal Fellow Network. My name is Nathan Hellman and I am presently a Nephrology Fellow at the Massachusetts General/Brigham & Women’s Hospital Combined Fellowship Program. I am in the midst of my first (clinical)…