A Primer on Primary Hyperoxaluria

Primary hyperoxalurias are a group of autosomal recessive disorders characterized by excess hepatic oxalate production and reduced kidney excretion. They are classified into three types based on their enzymatic defect in glyoxylate metabolism Type 1 (80%): alanine glyoxylate…

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Prune Belly Syndrome and Kidney Disease

Prune Belly Syndrome (PBS) is a very rare (3.8/100,000 live births) congenital disease that predominantly affects males. PBS is characterized by a triad of Anterior abdominal wall muscle deficiency  Urinary tract abnormalities Bilateral cryptorchidism.  Termed prune belly due…

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