Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
There’s no such thing as a contraction alkalosis
We recently discussed an excellent paper on the classification of metabolic alkalosis. The three suggested subtypes were primary and secondary stimulation of collecting duct ion transport and exogenous alkali administration. Another interesting editorial was just published in JASN…
Extend Medicare Coverage for Kidney Transplant Patients!
Currently many kidney transplant recipients lose their Medicare coverage 36 months after receiving a transplant. In some cases these individuals are then unable to afford the cost of anti-rejection medications and subsequently lose their kidney. When this happens…
Lead Nephrotoxicity
I saw a patient in the clinic who was referred for evaluation by his PCP with CKD, a bland urine sediment and a history of hyperuricemia and gout. He had no history of diabetes or hypertension and had…
A picture is worth…
Often on rounds with medical students or housestaff we will review why a serum creatinine of 0.8 mg/dl in a 40 year old athlete… may mean a much higher creatinine clearance than a creatinine of 0.8 mg/dl in…
Femoral versus Jugular: part three
Previous posts have discussed various iterations of the cathedia study, a study comparing femoral and jugular placement of dialysis catheters in patients in the ICU. As mentioned before, the femoral route was not associated with a higher rate…
In a Few Words
“A doctor, like a writer, must have a voice of his own, something that conveys the timbre, the rhythm, the diction, and the music of his humanity, that compensates us for all the speechless machines.” -Anatole BroyardIntoxicated by…
Azathioprine in pregnancy
We recently discussed this issue in conference and I thought it might be worth sharing a few interesting points: Azathioprine is normally converted to the active metabolite 6-mercaptopurine. However, in pregnancy the placenta can metabolize azathioprine to thiouric…
Cell Polarity and Cystic Diseases
There was an interesting article and accompanying editorial in JASN this month about the role of polarity in the development of cystic renal diseases. The maintenance of epithelial cell polarity is vital for the normal functioning of the…
From the RFN archives: The Brenner Hypothesis
The Brenner Hypothesis–developed by Barry Brenner of the Brigham and Women’s Hospital, author of the well-known Brenner & Rector “The Kidney” textbook–states that individuals with a congenital reduction in nephron number have a much greater likelihood of developing…
Hold the potassium
It was not an unusual event during my clinical fellowship to get a call from the cardiac team asking for dialysis in a patient with hyperkalemia and acute renal failure. On a few occasions the hyperkalemia seemed disproportionate…