Pregnancy and ACE inhibitors

Treating hypertension on pregnancy sometimes feels a little like going back in time. As Nate posted previously, the list of anti-hypertensives that are considered safe in pregnancy is relatively short – first line agents include labetalol, hydralazine, methyldopa…

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Cold and OTCs in Transplantation

Winter season arriving and you might see a couple of transplant patients with colds… Immunosuppressants have the potential to interact with OTC meds used to treat common colds and coughs, which can lead to alterations in the degree…

Entrapment

An 18 year-old girl with end stage renal disease secondary to focal segmental glomerular sclerosis had a double cuff flex neck peritoneal dialysis (PD) catheter uneventfully inserted in order to begin dialysis. Ten days after this procedure, following…

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Renal disease and HIV

Perhaps the most renowned renal disease associated with HIV infection is the collapsing variant of FSGS. This typically presents with the nephrotic syndrome and has been associated with relatively advanced HIV infection, with low CD4 counts and higher…

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The Brinicle

The normal saline we use in the hospital contains 9 grams of sodium chloride per liter of water. If you look on the bag you will see 0.9% which is the mass concentration expressed as g/dl (0.9 grams…

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Obese mice?

Recently there was a very interesting series in three parts in the online magazine Slate.com concerning the use of mice and rats as surrogates for humans in animal studies. Anyone who has worked with mice in the lab…

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