Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Tell me who your friends are and I will tell you who you are: NaHCO3 isn’t NaCl
When managing patients with metabolic acidosis, some nephrologists are afraid of prescribing NaHCO3 because of the potential adverse consequences of increasing ECF volume and worsening blood pressure. However, there is significant evidence that the kidneys handle NaCl in…
Blast from the past: the hepatorenal reflex revisited
How does sodium retention occur in liver cirrhosis? Most of us accept Schrier’s peripheral arterial vasodilation hypothesis. This hypothesis postulates that overproduction of vasodilatory substances in the splanchnic circulation in cirrhosis leads to splanchnic pooling and decreased “effective”…
The organization is key
There are a number of glomerulopathies that feature organized deposits of nonbranching fibrils, some more common than others. The diseases make their first major separation into Congo Red positive (amyloid) and Congo Red negative categories. Amyloid fibrils are…
NKF Spring Clinical Meeting – Calcium reabsorption
Here are some points from one of the cases presented at the electrolyte workshop this afternoon: The major teaching point was that the reabsorption of calcium closely follows that of sodium. Therefore, in sodium avid states, calcium tends…
NKF Spring Clinical Meeting – BP in CKD
I attended a very interesting talk from Dr Bakris today on the latest approaches to BP targets in the CKD population. The highlights are nicely illustrated in a systematic review published in the Annals this year. They searched…
NKF Spring Clinical Meeting – IgA
The NKF Spring Clinical meeting started today in Las Vegas. I thought I’d share of the interesting highlights from some of the talks I’ve attended. This post relates to Dr Appel’s lecture on IgA nephropathy, where he described…
Post-transplant malignancy 101
What are the most common type of cancers in kidney transplant recipients? The three most common cancers are: non-melanoma skin cancers, Kaposi’s sarcoma and non-Hodgkin lymphomas. Compared to the general population, the risk of squamous cell carcinoma is…
Thirst and xerostomia
One of the major problems we struggle with in haemodialysis patients is excess, volume, inter-dialytic weight gain and ultrafiltration. Despite constant reminders by nursing staff, physicians and nutritionists, patients seem to find it extremely hard to restrict their…
Are we finally getting thE kNaCk of edema in nephrosis?
Mechanisms of edema formation in nephrotic syndrome (NS) are controversial. The traditional underfill hypothesis has come under heavy fire, and there are now many clinical and experimental observations that contradict it. The overfill hypothesis has now captured the…
Webinar: FHN Daily Trial and NxStage Freedom Study
The recent publication of the landmark FHN Daily Trial was a step forward in our understanding of dialysis care. One of the authors, Dr. Brent Miller from Washington University School of Medicine in Saint Louis, is giving a…