Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Seldinger Technique
One of the many pleasures of nephrology fellowship is learning how to put in temporary hemodialysis lines safely and efficiently using the Seldinger technique (the Swede is seen to the left). As an intern I constantly said to…
IgG-4 associated kidney disease
We heard a very interesting presentation today on autoimmune pancreatitis and concurrent systemic disease. The pathogenesis is felt to be related to IgG-4 producing plasma cells, and has now been linked to numerous systemic disease manifestations. The case…
Noninvasive Control of Uremic Bleeding
We frequently receive requests to dialyze patients with moderate renal failure who are bleeding due to the concern that uremia may be contributing to failure to control blood loss. Patients with renal failure do have an increased tendency…
Getting to the heart of the matter: Anti-PLA2R and MN
A 53-year-old Caucasian male presented with pulmonary embolism, and was found to have nephrotic syndrome. A kidney biopsy showed membranous nephropathy (MN). The disease progressed despite treatment and six years later, the patient underwent a pre-emptive living unrelated…
Lactate gap in ethylene glycol toxicity
From Brindley P.G et al., CMAJ 4-10-07, 176(8) pg1097-1099 When making a decision about urgent dialysis it is important to have an much information as quickly as possible. In suspected ethylene glycol toxicity time is of the essence….
Hepatorenal Disease – Beyond the syndrome
In general, when we are asked to evaluate a patient with liver disease for the development of acute renal failure, the three top differentials are usually: true hepatorenal syndrome, a prerenal picture (often 2/2 overdiuresis) and ATN. Cholemic…
Hyperuricemia; treatment indications beyond gout?
What do you do when a patient with long standing CKD happens to have a uric acid level of 10mg/dl but has never had gout? Do you treat? Hyperuricemia occurs when an imbalance exists between uric acid production,…
Idiopathic MPGN and its subtypes. Or: I’m going to need the whole bottle to get through this
I recently evaluated a young patient for kidney transplant who had been diagnosed at age 13 with MPGN III. He had a slow reacting C3NeF, low C3, normal C4, low terminal complement levels, and by biopsy had paramesangial…
Post-transplant HUS
A young patient was recently transferred to our service for evaluation of acute renal failure that had developed many years following a liver transplant for PSC. She had presented to another institution with nausea, vomiting, fevers and a…
Are troponin levels useful in ESRD?
I recently admitted a dialysis patient to a general medicine service for shortness of breath. When receiving signout from the ED resident, she told me that his troponin T was elevated, but since he had had prior high…