Very interesting results from last week’s poll, in which the question asked was essentially, “Do you believe that steroids are effective in the treatment of AIN?” The vote was generally split 50-50; that is, about half of individuals…
I was taught the rule of 6’s when it came to using opiates in dialysis patients: they’re metabolized by hepatic glucuronidase to 6-glucurinides (e.g. morphine 6 glucuronide or M6G) these metabolites are renally excreted, increasing the half-life to…
Restless legs syndrome (RLS) is one of the potential neurologic complications associated with CKD or ESRD, though it can also occur independently of kidney dysfunction, with some cases of familial transmission documented (though no gene has yet to…
There is a good review article in this month’s NEJM entitled “Use of Diuretics in Patients with Hypertension” by Ernst and Moser which focuses predominantly on the thiazide class of diuretics. The thiazides are considered a FUNCTIONAL rather…
One of the things I was definitely grateful for at this year’s Thanksgiving table: I’m not on-call and can spend the holiday with my family! Best wishes to those renal fellows working hard on this holiday. Poll Results…
In my experience, it’s unusual to perform a transplant nephrectomy in a patient who has returned to dialysis in the absence of a ‘hard’ indication such as macroscopic hematuria or severe symptoms suggestive of rejection or infarction. There…
One of the hallmarks of autosomal dominant polycystic kidney disease (ADPKD) is hypertension. True, most patients with advanced kidney disease get hypertension anyways–but often the degree of hypertension in ADPKD patients seems to be especially high. Is there…
Very cool project: The Nephrology Oral History Project. On their homepage you can access interviews with 14 different nephrologists who practiced during the early days of dialysis, as early as the 1950s and 1960s. It’s well-organized in that…
It’s the weekend, I need to decompress from the boards. Here’s some random kidney-related clips. The first is pretty bizarre. This next one is pretty basic, but the animation is good.
I saw an interesting case yesterday. A 71 year old male, CKD III with a syndrome suggestive of chronic tubulointerstitial disease (U/A trace proteinuria only, disproportionate anemia, mild cortical thinning on ultrasound, normal-appearing vasculature on ultrasound). He had…