Aquaporins and the Kidney

The discovery of aquaporins–the protein family of water channels which regulate water transport in the kidney and many other tissues–was considered significant enough to win the Nobel Prize in Chemistry for Peter Agre in 2003.   The aquaporins…

Re-Evaluating the Ca x P Product

Heard an excellent presentation at our Renal Grand Rounds today by Dr. Charles O’Neill of Emory University, regarding the process of pathologic calcification in CKD/ESRD patients. One of the points I took away from this talk is that…

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Secondary AV Fistulas

Since I’m presently trying to make it through the most recent ish of NephSAP–their first-ever issue of “Interventional Nephrology”–I’ll do another access-related post. A “secondary AV fistula” refers to a fistula created after a pre-existing graft or fistula…

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Osmotic Nephrosis

“Osmotic nephrosis” is a term which describes a common form of renal tubular injury in response to hyperosmolar substances. It is especially relevant to iv contrast nephropathy, and was first observed in animals and human patients infused with…

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