Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Peritonitis Bugs
The two most common organisms causing PD-related peritonitis are (1) Staph aureus and (2) Pseudomonas. Certainly there are other causes–for instance fungal peritonitis (one of the indications for immediate catheter removal) and coagulase-negative Staph species (which usually responds…
Two Landmark PD Studies
How much peritoneal dialysis is enough? This question has been the basis of two major, landmark trials in the peritoneal dialysis community, the CANUSA study (named as such because it looked at PD patients in Canada and the…
Nuclear Medicine Renal Imaging
There are numerous different types of radionuclide imaging which are used in renal imaging–more commonly in pediatric than in adult patients, and as such my knowledge of these procedures as it pertains to adult nephrology patients has always…
cystic fibrosis & PKD
In order for renal cysts to grow in patients with polycystic kidney disease, it turns out this requires the pumping of chloride ion into the cyst lumen. This is carried out by the CFTR channel, the same chloride…
Plasma Exchange for Myeloma?
A question which comes up not infrequently during nephrology fellowship is whether or not to perform pheresis on patients with multiple myeloma. Once very much in vogue, the results of a fairly recent (Annals of Internal Medicine, 2005)…
Peritoneal Dialysis Color Coding
A quick one before the July 4th Weekend… Peritoneal dialysis solutions are often color-coded based on the dextrose concentration. Dextrose is used as the osmotically-active agent. As it is partially absorbed, patients with diabetes have to watch out…
peritoneal equilibration test (PET)
Not all peritoneal membranes are created equally. The peritoneal equilibration test (PET) is a standardized method for assessing peritoneal membrane function, and is used for tailoring an appropriate, individualized PD prescription. The test is based on the fact…
Femoral versus Intrajugular Dialysis Catheters: the Debate Continues
A recent JAMA article (Parienti et al, JAMA 2008) was presented in journal club today which involved a randomized control trial looking at infectious and other complications seen in patients with acute kidney injury in an ICU who…
HNF-1B Mutations & Kidney Disease
Although mutations in the gene HNF-1beta (or TCF2) were originally discovered in patients with mature-onset diabetes of the young (MODY), patients with these mutations more commonly present with a variable renal phenotype. Interestingly, a study by Egdhill et….
Hepatitis B Virus & Renal Disease
Hepatitis B–a disease which in the U.S. is on the decline due to regular childhood vaccinations–has a variety of interesting associations with renal disease. There are three distinct glomerular diseases with which the hepatitis B virus is associated….