Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Staghorn Calculi
Staghorn calculi are upper urinary tract kidney stones which involve the renal pelvis and involve at least two of the calyces. They are formed in the setting of an alkaline pH and urease-producing micro-organisms, which leads to the…
Renal Assist Device
I reviewed a paper in our Renal Journal Club today–Tumlin et al, Efficacy and Safety of Renal Tubule Cell Therapy for Acute Renal Failure in a recent 2008 issue of JASN–which tests a novel device termed the “Renal…
DCOR Trial
The DCOR Trial was a Genzyme-funded randomized control trial–somebody recently told me the largest ever conducted in a dialysis population–designed to compare the phosphate binder sevelamer (Renagel) with Ca-containing phosphate binders (calcium acetate a.k.a. Phoslo or calcium carbonate)….
Direct Versus Indirect T-cell Stimulation
When somebody receives a kidney transplant, the current strategy is to hit them hard with immunosuppression initially–using potent medications such as thymoglobulin, Cell-Cept, steroids, and tacrolimus at higher levels–and that medication can generally be tapered to much lower…
Hereditary Amyloidosis
I saw a patient in Transplant Clinic today with a strong family history of chronic kidney disease requiring dialysis and periodic fevers. She was coming to the Transplant Clinic because she wants to be considered for a potential…
DDx for Acute Kidney Injury in Myeloma Patients
Multiple myeloma and renal disease often go hand-in-hand, and it has a differential diagnosis which is fascinating in terms of its breadth. Although we often diagnosis many of these patients with “cast nephropathy”, my suspicion is that some…
CVVH Basics
CVVH (continuous venovenous hemodialysis) is the form of CRRT (continuous renal replacement therapy) used in our hospital. Although most studies have not shown a mortality benefit in patients treated with intermittent hemodialysis versus those treated with CVVH, in…
The Ponticelli Protocol
When one is just beginning as a nephrology fellow, it may seem as if all the major glomerular diseases (e.g., membranous nephropathy, FSGS, lupus, etc) are all treated with the same protocols and same immunosuppressive agents: steroids, Cytoxan,…
Tonsillectomy for IgA Nephropathy?
IgA Nephropathy is the most common cause of glomerulonephritis globally. It is especially common in Japan, although some of this prevalence may be due to increased screening (all school children undergo a screening urinalysis as part of their…
Ecstasy-Induced Hyponatremia
The recreational drug ecstasy (MDMA) is known to result in hyponatremia–which has been reported to result in seizures and death–has a multifactorial mechanism which is interesting. MDMA is associated with elevated ADH levels. In addition, individuals who take…