The Ponticelli Protocol

When one is just beginning as a nephrology fellow, it may seem as if all the major glomerular diseases (e.g., membranous nephropathy, FSGS, lupus, etc) are all treated with the same protocols and same immunosuppressive agents: steroids, Cytoxan,…

Ecstasy-Induced Hyponatremia

The recreational drug ecstasy (MDMA) is known to result in hyponatremia–which has been reported to result in seizures and death–has a multifactorial mechanism which is interesting. MDMA is associated with elevated ADH levels. In addition, individuals who take…

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Uremic Pericarditis

We are all familiar with “uremic pericarditis” as one of the standard indications for initiating dialysis, and the number of physical exams with a negative cardiac rub I have documented this year is truly impressive. Which is why,…

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the MEPEX Trial

When you are called at 5pm to start pheresis on a patient with Wegener’s granulomatosis who is already on dialysis…there is a certain part of the renal fellow which wants to say, “Come on–the dude is already on…

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