Kidney Comics: Membranous Nephropathy
We are proud to announce a new series on RFN called Kidney Comics. This series is is led by Dr Momen Abbasi and will cover various topics in nephology. Let us know if you have any ideas or…
Culprit Antigens in Membranous Nephropathy: Growing by the Day
Mythri Shankar, MD, DNBAssistant Professor of NephrologyInstitute of Nephrourology, Bengaluru, India@nephromythri Membranous nephropathy (MN) is a common cause of nephrotic syndrome in n adults predominantly presenting in the 5th decade of life. The incidence of MN in adults…
Kidney Biopsy of the Month: Membranous Nephropathy
Demographics Membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome in Caucasian adults above 40 years. However, it can occur in different ages and ethnicities. The incidence was estimated about 8-10 cases per one…
Landmark Trials in Membranous Nephropathy
Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in the Caucasian adult population with an estimated incidence of 8–10 cases per 1 million and commonly seen in males above the age of 40. It is…
Evolution of PLA2R as biomarker, diagnostic tool and prognostic indicator in Membranous Nephropathy
Membranous nephropathy is among the most common causes of the nephrotic syndrome in non-diabetic adult. It is an immune complex mediated disease which occurs when circulating antibodies permeate the glomerular basement membrane and form immune complexes with epitopes…
The use of Rituximab in Kidney Disease
Rituximab, the monoclonal chimeric anti-CD20 antibody, is an effective B-Cell depleting agent and continues to gather data for its use in a wide range of conditions relevant for the Nephrologist. It was also a pre-season favourite in the…
Update on Membranous Nephropathy
U Penn established an annual one-day seminar in nephrology symposium. This year was titled “New Horizons in Nephrology: Updates in Glomerular Disease”. Dr. Beck from Boston University gave the update on membranous nephropathy (MN). Previously, we discussed his…
Image of the Month
A man in his early 60s was being treated for metastatic adenocarcinoma of the lung for 2 years. Recently, he had been complaining of increasing hemoptysis and a PET CT was performed which showed progression of his disease….
Getting to the heart of the matter: Anti-PLA2R and MN
A 53-year-old Caucasian male presented with pulmonary embolism, and was found to have nephrotic syndrome. A kidney biopsy showed membranous nephropathy (MN). The disease progressed despite treatment and six years later, the patient underwent a pre-emptive living unrelated…