Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Drug-resistant CMV Infection
CMV (cytomegalovirus) infection is quite common in the transplant population, and fortuantely the development and utilization of valganciclovir (Valcyte), an oral prodrug of ganciclovir, as a prophylactic agent has dramatically cut down on the number of CMV infections…
PKD Molecular Genetic Analysis
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is caused by the autosomal dominant transmission of mutations in one of two genes identified thus far: PKD1 (which accounts for about 85% of all cases and encodes for the polycystin-1 protein)…
the MEPEX Trial
When you are called at 5pm to start pheresis on a patient with Wegener’s granulomatosis who is already on dialysis…there is a certain part of the renal fellow which wants to say, “Come on–the dude is already on…
Recurrent FSGS after Transplant
There are many diseases which can recur following renal transplant: examples include IgA Nephropathy (which has a very high rate of recurrence on follow biopsy but is rarely clinically relevant in that it does not cause significant allograft…
Fattest Dialysis Patient Ever
There is an interesting paper in the literature which just came out–I have to admit that I’m a little biased since the senior author is my father, also a nephrologist–describing the dialysis of the most obese patient ever…
Diarrhea & common immunosuppressants
Did you know that diarrhea increases the absorption of Prograf (tacrolimus, FK506)? Drug levels must be monitored closely in this setting to avoid tacrolimus-induced allograft toxicity. Tacrolimus is even considered a cause of diarrhea by some, though its…
Aristolochic acid
Aristolochic acid is an herb used in many varieties of Chinese herbs and health supplements. Interestingly, it also can cause a severe form of interstitial nephritis which has been known by several names, most notably “Chinese herb nephropathy”…
Leflunomide
Leflunomide is a drug I’ve seen used with increasing frequency in the renal transplant world. Marketed under the trade name “Arava”, it is an immunomodulatory agent which works by inhibition of the enzyme dihydroorotate dehydrogenase, one of the…
Avastin-induced kidney injury
Avastin (bevacizumab) is one of the commonly used VEGF (vascular endothelial growth factor) inhibitors used to inhibit vascular neogenesis, a process which is required for growth of tumor. It has proven to be a valuable agent in a…
Wearable Artificial Kidney
The man on the left is Victor Gura, one of the authors on a 2007 Lancet paper demonstrating the efficacy of the wearable artificial kidney (WAK). The machine (which can perhaps be likened to deluxe version of Batman’s…