Multiple myeloma (MM) is the most common malignancy causing ESRD. Renal disease is frequently related to the characteristics of the monoclonal immunoglobulin produced, which can lead to 3 general pathological findings: “cast nephropathy’, light chain deposition disease or…
A number of years ago, I was at a lecture given by a transplant surgeon from London. He was discussing the dangers surrounding living unrelated kidney transplantation and he told the story of a member of a royal…
And now for something totally exciting—a post on water treatment in dialysis. Dr Daniel Coyne of Washington University gave a great review on this topic at the Brigham Renal Board Review course this week. Here is the basic…
A patient presented to the outpatient service with progressive renal insufficiency and sub-nephrotic range proteinuria. He had a long history of CMML with few blasts in his bone marrow aspirate but a peripheral white cell count that was…
This is a question we face quite often in the Nephrology clinic when we are commencing patients on high dose steroids for glomerular and other systemic inflammatory diseases. I came across a couple of interesting retrospective studies while…
When one is just beginning as a nephrology fellow, it may seem as if all the major glomerular diseases (e.g., membranous nephropathy, FSGS, lupus, etc) are all treated with the same protocols and same immunosuppressive agents: steroids, Cytoxan,…
As an intern, and I’m sure many can relate to this story, I remember trailing after the team, disheveled and exhausted as we rounded endlessly postcall one day. Our hospital had the county jail contract and as we…
Date for your diary Dr Zeidel and the MDIBL crew wish to invite all previous attendees to the Second Annual Reunion of the Mount Desert Island Biological Laboratory National Course for Renal Fellows. This is a great opportunity…
I’ve had the privilege of being a part of the care team for several patients who have participated in Stanford’s Immune Tolerance program here in Palo Alto. The idea behind the program is pretty cool: create chimerism (the…
We are frequently faced with patients on multiple anti-hypertensives still with poorly controlled BP levels. I learned some very interesting points on an article at CJASN from Dr Townsend on how to approach the management of those patients:…