Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Organophosphate poisoning … a rare cause of AKI?
A colleague of mine at another academic institution recently informed me about a patient that had been admitted to the ICU with organophosphate poisoning. In spite of aggressive treatment, the patient remained critically ill with multiorgan dysfunction and…
The great salt war; population-wide salt reduction
Population-wide salt reduction is gaining increased media and political attention over the last few years. The most notable example is the National Salt Reduction Initiative (NSRI) spearheaded by New York City Mayor Michael Bloomberg. This initiative was unveiled…
Cerebral salt wasting: is it all in the head?
I recently saw a patient in clinic who had sustained a head injury and developed hyponatremia that persisted after discharge. In his chart was a great deal of debate over the cause of his hyponatremia: SIADH or cerebral…
Preventing Chronic Rejection: Can it B?
For the past 5 years, alloantibody measurement has become a standard of practice in recipients of kidney transplants experiencing worsening allograft function. This week, I admitted a patient who had a rising creatinine and on biopsy mild-moderate interstitial…
Physiology of serum free light chains
Monoclonal gammopathies generally arise from an abnormal clone that has developed from a single cell of B-cell lineage. The monoclonal protein can be intact immunoglogulin (often associated with free light chain), free light chain (FLC) in isolation, or…
Monitoring the immune function: a shot in the dark!!
Almost every transplant clinic I have, one of my patients will ask about reducing his or her immunosuppression. This happened again this week. Needless to say that this is one of the most frustrating area in transplantation where…
TREAT or don’t treat? Future goals of anemia treatment…
Historically – before CHOIR and CREATE – Goals for anemia management were Hb level of 11-13 g/dl Iron saturation > 20% Ferritin >200. CREATE changed the tide which was followed by CHOIR. CREATE (Epo-β) had intent to treat…
The importance of perseverance in ANCA vasculitis
I saw a patient in clinic in follow up this week who was interesting. A 90 year old thoroughly delightful woman who presented last July with acute renal failure, creatinine rising from normal to 4.4 within a period…
Diuretic choice in decompensated liver disease
Spironolactone has long been favored in the setting of decompensated liver disease; the effective control of “secondary aldosteronism” is usually given as the reason for this in textbooks. However, this is like saying you should open a new…
Nephron number, not glomerular filtration rate
Nephrologists for many years have been able to accurately measure kidney function, a measure termed the glomerular filtration rate or GFR. To this end we have been the envy of many other specialties. However the GFR can be…