A second look at dilantin

The first time phenytoin was addressed as a blog on this site was on the one year anniversary of the inauguration of the RFN. I’d just like to bring it up again, because a question pertaining to phenytoin…

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Angiojet as a Cause of AKI??

The Angiojet Rheolytic Thrombectomy System is a medical device currently used to re-establish blood flow in a variety of settings. Briefly, a catheter is introduced into an area of thrombosis and a saline stream is directed towards the thrombus of…

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Ischemia-Reperfusion Models

The study of AKI/ATN has relied heavily on one particular animal model: the warm ischemia-reflow model (often referred to as “ischemia-reperfusion injury”), in which one of the renal arteries is transiently ligated off for a set period of…

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Transplant Glomerulopathy

As acute rejection rates continue to fall, causes of late allograft loss, such as transplant glomerulopathy (TG), become increasingly important. TG should spring to mind when you encounter a renal transplant recipient who develops heavy proteinuria and progressive…

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Atypical HUS & Orphan Drugs

Atypical HUS refers to hemolytic uremic syndrome which occurs without E. coli 0157:H7-induced diarrhea as the inciting event. There are many causes of atypical HUS: calcineurin inhibitors, HIV, pneumococcal infection and rare genetic diseases are all on the…

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