Back from the 2009 ASN Meeting in San Diego! I’ll admit to a few lapses in blogging, but the meeting kept me pretty busy. Thanks to everybody who stopped by the Renal Fellow Network poster and their encouraging…
Peroxisome proliferator-activated receptors (PPARs) are transcription factors that play a critical role in regulating lipid and glucose metabolism, cell growth and cell differentiation. PPAR alpha is expressed in highly metabolically active tissues (alpha = active), including the PT…
Renal Fellow Network is taking its show on the road…to the ASN meeting in San Diego, CA! I’m presenting a “Renal Fellow Network” poster at the poster session on Saturday, 10/31 (SA-PO2863) if anybody would like to…
Though this is to some degree controversial, volume expansion with normal saline has been associated with the development of a hyperchloremic, non-anion gap metabolic acidosis. What are the mechanisms associated with saline expansion-induced metabolic acidosis? The rationale for…
Get your flu shots, everyone! Renal Fellow Network recently had to take an H1N1-sponsored weekend off, and I strongly suggest getting the vaccine if available to you; this bug is no fun at all. I’ve written about the…
I’ve had to revise the renal biopsy complication rates that I’m quoting my patients after reading this review. – Technically, complications occur in 7.4% to 19.5% of patients. These mostly consist of self-limiting macroscopic hematuria or a peri-renal,…
Final results of last week’s Renal Fellow Network poll: There seemed to be general agreement that volume expansion with isotonic saline is definitely effective, and many individuals also selected the isotonic saline + N-acetylcysteine combination. Interestingly, only 23%…
Here are a few important guidelines for prescribing RRT in the Neuro ICU gleaned from this review. First off, a recap of the physiology… Intracranial pressure increases are buffered by CSF, such that increased ICP leads to increased…
The ability to adequately suppress the immune system and prevent allograft rejection has been a true success story over the past several decades. With the advent of drugs such as calcineurin inhibitors, induction agents such as thymoglobulin, azathioprine…
Hypouricemia is defined as a serum uric acid level less than 2mg/dL. Although it is generally considered benign, hypouricemia has been associated with several important conditions relevant to nephrologists, including acute kidney injury, uric acid nephrolithiasis, and SIADH…