Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Complement Levels & Glomerulonephritis
Although the complement cascade is an essential aspect of the response to infection, it unfortunately can be activated by a variety of means in several types of kidney disease. In common day clinical practice, most of the time…
Secondary Causes of Membranous Nephropathy
Although the majority of membranous nephropathy falls under the “idiopathic” category, there are a variety of causes of secondary membranous nephropathy. It is quite important to eliminate these entities as possible diagnoses, as the treatment for secondary membranous…
Serum Amyloid P prevents renal fibrosis
Congratulations to my colleague at the Brigham, Jeremy Duffield, who made the cover of Science this week for demonstrating human Serum Amyloid P (hSAP) potently inhibits fibrosis in two independent models of renal fibrosis. hSAP is a naturally…
Results of Kidney Biopsy Poll
The results from last week’s Poll of the Week are in, and in general, a majority of individuals (64%) felt that their training programs did a good job of teaching them the art of the renal biopsy, while…
TREAT Trial
The TREAT trial was one of the bigger stories to emerge from this years ASN. This was a large, multicenter trial of darbepoeitin (Aranesp) vs. placebo in 4000 predialysis CKD patients with type 2 diabetes and anemia. The…
The Uroplakins
We are taught that water is freely diffusable via cell membranes–even in the absence of aquaporin function, there are usually some water molecules which traverse the lipid bilayer. However, there are tissues within the human body which must…
On the mechanism of thiazide-induced hypocalciuria
Back from the 2009 ASN Meeting in San Diego! I’ll admit to a few lapses in blogging, but the meeting kept me pretty busy. Thanks to everybody who stopped by the Renal Fellow Network poster and their encouraging…
PPAR’s: “Peptide Protectors Against Renal Failure?”
Peroxisome proliferator-activated receptors (PPARs) are transcription factors that play a critical role in regulating lipid and glucose metabolism, cell growth and cell differentiation. PPAR alpha is expressed in highly metabolically active tissues (alpha = active), including the PT…
Renal Fellow Network Comes to ASN…
Renal Fellow Network is taking its show on the road…to the ASN meeting in San Diego, CA! I’m presenting a “Renal Fellow Network” poster at the poster session on Saturday, 10/31 (SA-PO2863) if anybody would like to…
“Dilutional Acidosis”
Though this is to some degree controversial, volume expansion with normal saline has been associated with the development of a hyperchloremic, non-anion gap metabolic acidosis. What are the mechanisms associated with saline expansion-induced metabolic acidosis? The rationale for…