Kidney Transplant Allocation Policy

I heard a great talk today detailing possible changes in store for the national policy for kidney transplant allocation, as set forward by the Organ Procurement and Transplanation Network (OPTN) (the organization which helps administer UNOS).   The current…

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Schistosomiasis and Renal Disease

Schistosoma species–also known as blood flukes and bilharzia–can cause some interesting forms of renal disease. Although this is not so common in the United States, it is a very common public health problem in Africa and Asia. Chronic…

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Route of EPO Administration

In the U.S., erythropoietin is typically delivered as 3x/week intravenous injections in the ESRD population. This turns out to be a fairly significant cost, as Medicare-related payments for EPO comprise about 25% of the ESRD budget, which itself…

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Renal Complications of ESWL

Extracorporeal shock wave lithotripsy (ESWL), invented during the 1980s in Germany, uses concentrated pulses of sound waves to break up kidney stones too large to pass on their own into smaller pieces, which will then have a chance…

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From the RFN Archives: Drug-Induced ANCA

A subset of patients with ANCA-associated vasculitis have drug-induced ANCA disease. There are a few features of drug-induced ANCA disease which set it apart from “idiopathic” ANCA disease, but overall the clinical symptoms are similar. Drug-induced ANCA almost…

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THAM

Have you ever given THAM (tromethamine)? For whatever reason I was completely unfamiliar with the drug as a resident, but it is given not infrequently in the surgical ICU’s in the hospitals in which I’ve worked as a…

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