Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
The Hatfields, the McCoys, and von Hippel Lindau Syndrome
I saw a patient in my clinic today with the diagnosis of von Hippel-Lindau Disease. She has a Cr in the mid 2’s as a result of prior vascular disease as well as being status-post nephrectomy for a…
cholemic nephrosis?
Amongst the given differential diagnosis for acute renal failure in liver disease is an entity termed “cholemic nephrosis.” It is debatable as to whether or not this actually exists or represents part of the spectrum of hepatorenal syndrome…
Tamm-Horsfall Protein
It took me until just recently to realize this, but the Tamm-Horsfall protein and uromodulin are two names for the same gene. As we all know, Tamm-Horsfall protein (discovered by Tamm and Horsfall in 1950) is the…
‘Shrooms and Renal Failure
While toxic mushroom ingestions are generally known for their ability to cause acute liver failure, certain varieties of mushrooms can also result in acute renal failure. One such type of mushroom is Amanita smithiana, (shown at left) which…
Microhematuria in Potential Kidney Donors
The key aspect of the workup for a potential kidney transplant donor is ensuring that donation does not result in future health problems for the donor. For the most part, this boils down to determining whether or not…
TRP Channels in Nephrology
The TRP (transient receptor potential) family of proteins is a group of related ion channels which is becoming increasingly relevant to the field of nephrologists. The TRPs are cation channels which are responsible for moving Ca2+ and Mg2+…
Reverse Osmosis
Reverse osmosis (RO) is a critical aspect of providing the large volume of relatively purified dialysate water to dialysis patients worldwide. If you’ve never taken a peek at the water treatment room in your hospital’s dialysis unit (it…
Plasma Exchange Nuts & Bolts
There are many indications for plasma exchange in nephrology: some common ones include antibody-mediated rejection of a kidney transplant, Goodpasture’s, ANCA-associated vasculitis, and TTP–all of which are commonly associated with loss of renal fellows’ sleep–that is, you may…
Renal Vein Thrombosis
Renal vein thrombosis is a thrombotic occlusion of one or both renal veins. Its most common cause is nephrotic syndrome, which is a hypercoaguable state though to be due at least in part to loss of the anticoagulant…
Urine Anion Gap
The urine anion gap is calculated as follows: [urine Na] + [urine K] – [urine Cl]. Think about the urine anion gap much as you think about the serum anion gap. The urine anion gap is really…