Anti-Nephrin Antibodies in Minimal Change Disease
Approach to the Patient with Peritoneal Dialysis Catheter Dysfunction- Part 1
Want to write a case report? RFN has you covered with a list of journals to choose from
Have a Nephrology Question? There Might Be A #Tweetorial For That!
Conferences, Courses, & Grants
FOAMed
Interventional Nephrology Series
Focus on Point-of-Care Ultrasound in Nephrology (POCUN) Series
Kidney Biopsy of the Month Series
Plasma Exchange Nuts & Bolts
There are many indications for plasma exchange in nephrology: some common ones include antibody-mediated rejection of a kidney transplant, Goodpasture’s, ANCA-associated vasculitis, and TTP–all of which are commonly associated with loss of renal fellows’ sleep–that is, you may…
Renal Vein Thrombosis
Renal vein thrombosis is a thrombotic occlusion of one or both renal veins. Its most common cause is nephrotic syndrome, which is a hypercoaguable state though to be due at least in part to loss of the anticoagulant…
Urine Anion Gap
The urine anion gap is calculated as follows: [urine Na] + [urine K] – [urine Cl]. Think about the urine anion gap much as you think about the serum anion gap. The urine anion gap is really…
Bactrim & elevated creatinine
The antibiotic Bactrim is frequently associated with an increase in creatinine shortly after starting it. While Bactrim is a not uncommon cause of acute interstitial nephritis (AIN), the most frequent reason for a Bactrim-associated creatinine increase is actually…
Old Dialysis Video
Check out this video I found of the alleged first-ever home dialysis patient in England. Very civilized, except for the fact that it looks like the patient is using a permanent femoral dialysis catheter–something which would be used…
CKD in the Elderly
A current controversy in the CKD community involves definitions of CKD in the elderly. The issue is not trivial: were we to apply the standard KDOQI definitions of CKD staging, using the MDRD equation to estimate GFR, this…
cisplatin-induced acute kidney injury
At the Brigham and Women’s Hospital & the Dana Farber Cancer Institute, there is an ongoing trial of using pneumonectomy and injected, heated cisplatin into the pleural space for patients with malignant mesothelioma, a condition with an overall…
mesanagial cells
Mesangial cells–which historically have received less attention than their more “sexy” neighbor cell types of the glomerulus such as podocytes & endothelial cells–are actually quite interesting. They were originally seen as having purely a “matrix” function–that is, serving…
Gamblegrams
Heard a very good Renal Grand Rounds yesterday from visiting professor Michael Emmett, currently chair of the Dept. of Medicine at Baylor, regarding the anion gap. Amongst the pearls I took away from his lecture: 1. “Gamblegrams” (left),…
Why does hypomagnesemia result in refractory hypokalemia?
We’ve known this medical factoid since we were medical students: you can’t successfully replete a potassium-depleted patient if they have low magnesium levels. But what is the mechanism by which this occurs? One possible explanation is put forth…