1) Icodextrin sometimes causes a desquamating rash on the palms and soles. 2) Sirolimus, five side effects to watch 1) Poor wound healing 2) Lung toxicity 3) Hyperlipidemia 4) Proteinuria 5) Anemia/Thrombocytopenia. 3) Classic EM finding in post infectious GN: Large…
One of the big stories at the ASN this year was the announcement of the results of the TEMPO trial which were simultaneously published in NEJM. It has been known for some time that ADH is implicated in…
Obituary from the NYT. In 2010, RFN on the passing of Ronald Herrick.
In a previous post, we discussed the dangers of subgroup analyses. Specifically, performing increasing numbers of post-hoc subgroup analyses increases the risk of a type 1 error while the inevitable reduction in numbers tested in subgroup analyses decreases…
1) Monoclonal Immunoglobulin Deposition Disease breakdown – 80 to 90% LCDD, 10 to 20% LHCDD, <5% HCDD. 2) Small studies suggest tamoxifen and steroids may be of benefit in management of Encapsulating Peritoneal Sclerosis in patients on PD. 3) Sodium restriction…
Following on from yesterday’s post about turtles who may have a taste of urine in their mouths, here’s an interesting historical diversion about doctors who, in the past, intentionally drank urine to diagnose disease. An article in Scientific…
Better known as a delicacy in the Far East, the Chinese softshell turtle has generated some interest in the Nephrology world because of its unusual means of urea elimination. A paper was recently published in the Journal of…
It doesn’t take much to get me to take a trip to San Diego so when the opportunity came up to attend this year’s Home Dialysis University conference I booked my flight. Having lived in San Diego for…
Fluid therapy is essential in ICUs and not surprisingly there is still much controversy about which fluid to use, how much and when. Nephrologists often roll their eyes at other subspecialty’s preferences, e.g. surgeon’s preferences for Ringers, citing…
1) Alkaline urine encourages calcium phosphate nephrolithiasis. Three predisposing factors to watch for – 1) distal RTAs 2) Acetazolamide 3) Topiramate. 2) IgA nephropathy, common in Asians and Native Americans, rare in African Americans. 3) Stay alert for triphasic pattern of…