Image of the Month

The renal services were consulted on a man in his late 70s with a distant history of colon cancer, recent pneumonia and NSTEMI, for investigation of worsening renal function. He had sub-nephrotic range proteinuria (2-3 g/24 hours) and…

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Diabetic Nephropathy, or not?

A man in his 30s with a history of type 1 DM and chronic hypokalemia was referred to the renal clinic for investigation of CKD. His creatinine was 1.8g mg/dl.  His DM was well controlled without any evidence…

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Phosphorous Binder Equivalent Dose

Ever encountered this situation?  You’re going about your daily business and discover that one of your patients on hemodialysis has an elevated phosphorous. You skim through the list of prerequisites and see that yes, the nutritionist has been…

Pearls for Boards

1) In diabetic glomerular disease you can see linear staining of GBMs with IgG, Kappa and Lambda. 2) The three C3 immunoflourescence patterns of post strep GN 1) Starry Sky (most common) 2) Garland (less common) 3) Mesangial (resolving Starry…

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Visitor Poll

Every once in a while we like to get an idea of who our audience is. As a result, we have started a poll which will remain open for the next 7 days. The website was originally started…

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Fruit Flies and Kidney Stones

Developing accurate animal models of human diseases is a well-established research goal but a recent paper reporting a new animal model of nephrolithiasis caught my attention. Kidney stones are an important cause of morbidity and dealing with them…

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Image of the Month – Pathology

A 60 year-old woman with a longstanding history of hypertension, scleroderma and MGUS presented to the emergency room with diarrhea, vomiting and AKI (creatinine increased from baseline of 1.5mg/dl to 3.1mg/dl). She had a distant history of membranous…

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