Image of the Month – Pathology

A 60 year-old woman with a longstanding history of hypertension, scleroderma and MGUS presented to the emergency room with diarrhea, vomiting and AKI (creatinine increased from baseline of 1.5mg/dl to 3.1mg/dl). She had a distant history of membranous…

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Mg & K

It is well known that hypokalemia does not correct easily if it is accompanied by hypomagnesemia. A medical student I met looked into this topic and found a “Science in Renal Medicine” article. According to this article, one of…

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Pearls for Boards

1) Icodextrin sometimes causes a desquamating rash on the palms and soles. 2) Sirolimus, five side effects to watch 1) Poor wound healing 2) Lung toxicity 3) Hyperlipidemia 4) Proteinuria 5) Anemia/Thrombocytopenia. 3) Classic EM finding in post infectious GN: Large…

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Aquaretics and PCKD

One of the big stories at the ASN this year was the announcement of the results of the TEMPO trial which were simultaneously published in NEJM. It has been known for some time that ADH is implicated in…

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Miracle Drug – Part 2

In a previous post, we discussed the dangers of subgroup analyses. Specifically, performing increasing numbers of post-hoc subgroup analyses increases the risk of a type 1 error while the inevitable reduction in numbers tested in subgroup analyses decreases…

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Does that taste bad? – Part 2

Following on from yesterday’s post about turtles who may have a taste of urine in their mouths, here’s an interesting historical diversion about doctors who, in the past, intentionally drank urine to diagnose disease. An article in Scientific…

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