Bone Scan for Diagnosis of Calciphylaxis?

Calciphylaxis (also called calcific uremic arteriolopathy) is a syndrome of vascular calcification, thrombosis, and necrosis, occurring almost exclusively in ESRD patients.  The diagnosis is typically achieved by clinical exam–demonstrating painful, necrotic, and sometimes ulcerating lesions usually on the…

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The Proteinuria Controversy

One of the largest controversies in the field of proteinuria/nephrotic syndrome research derives from a 2007 Kidney International paper published by Russo et al. Briefly stated, the authors suggest the paradigm-shifting idea that the glomerulus filters massive amounts…

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The Kidneys as Food

The French, renowned for their culinary excellence, pride themselves on being able to include every part of the cow in a tasty dish. Regrettably, this includes finding uses for the many internal organs, one of the more challenging…

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Nail-Patella Syndrome

Too long have I seen the “Nail-Patella Syndrome” included in the differential diagnosis of renal disease without understanding anything about it…that ends today! The Nail Patella Syndrome (NPS), also referred to as Hereditary Onychoosteodysplasia, is an autosomal dominant…

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Death by Soy Sauce?

Bizarre case of hypernatremia:  a suicide attempt by a 73 year-old Japanese man in which the individual drank massive amounts of soy sauce.  According to this 2006 Neurology paper by Machino et al, the patient presented with vomiting,…

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