The past two weeks have been exciting for the field of regenerative medicine in nephrology. Two papers demonstrated the feasibility of developing kidney cells from human pluripotent stem cells. One from the USA by Dr Joseph Bonventre’s group…
For severe or refractory rejections, thymoglobulin/ATG is commonly employed in combination with steroids and B-cell targeted therapies when indicated. However, alemtuzumab could be more effective then thymoglobulin since it depletes not only T cells but also memory B…
An interesting study appeared in my email this morning examining the association between the use of iv iron and outcomes in hemodialysis patients with systemic infections. Current guidelines from all of the major societies suggest that if patients…
KDPI (kidney donor profile index) is a numerical measure that combines ten variables about a donor, including clinical parameters and demographics, to express the quality of the donor kidneys relative to other donors. It has been reported by…
Hemolytic uremic syndrome is a thrombotic microangiopathy characterized by thrombocytopenia, microangiopathic hemolytic anemia and renal impairment. Most cases (90%) are secondary to infections, such as E. Coli (serotypes O157:H7, O103:H2). For a more comprehensive review about aHUS, check…
A 31 year-old healthy male donated his kidney to his mother who had IgA nephropathy. Prior to donation, his creatinine was 1.08 mg/dl. One year after donation, his creatinine is 1.59 mg/dL. He was seeing in clinic and…
Washington University at St Louis will be holding the inaugural Midwest Transplant Symposium on October 16th and 17th 2015. This course is designed to be an in-depth review and update in kidney and pancreas transplant. 8.5 AMA PRA…
One day symposium on OncoNephrology: Cancer, Chemotherapy and the Kidney Where: Hofstra NSLIJ School of Medicine When Sept 26th, 2015 from 7:30AM to 4PM The conference will highlight and review the latest happenings in OncoNephrology This CME is…
Delayed graft function (DGF) after kidney transplant is associated with long-term allograft dysfunction. Niemann et al. (NEJM 2015;373:405) reported that therapeutic hypothermia reduced DGF (defined here as the requirement of dialysis in the recipient within 7 days after…
A few weeks ago, one of our pharmacists gave a comprehensive presentation about the potential nephrotoxicity of a variety of commonly used herbal, alternative and dietary supplements. He has a particular interest in this as he deals largely…