I had the opportunity to talk to Nate on several occasions when he would moonlight and I would be burning the midnight oil on call. Our conversations would run the gamut from our families, to life as a…

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Creatinine: A Cautionary Tale

In recent months I’ve been seeing a number of referrals for patients with creatinine values in the normal range but eGFR as reported by the lab at below 60ml/min. This is particularly the case in middle aged women….

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A Man’s Best Friend

I’m sure many of you have a pet dog. Well, as Rover quietly licks himself in the corner, few would believe that he may hold the key to unlocking the genetic secrets of human disease, as suggested by…

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Tamm-Horsfall Protein and Kidney Disease

Tamm-Horsfall protein (THP), or uromodulin, is a glycoprotein secreted by the renal epithelium, best known as the proteinacious framework of all urinary casts. It’s function in health is an enigma, but prevention of bacterial colonization of the urinary…

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