Dialysis in the Elderly

The rate of patients >75 years of age initiating dialysis has grown substantially in the U.S. over the past two decades.  This has to do with several factors, including improvements in medical technology enabling people to live long…

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Potassium-Sparing Diuretics

The potassium-sparing diuretics consist of the following 4 medications–only some of which (spironolactone & eplerenone in the list below) are structurally similar.   Spironolactone is an antagonist of the aldosterone receptor, which like other steroid receptors is an…

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The importance of residual renal function

A recent review in this month’s AJKD by Perl and Bargman describes the increasingly recognized importance of residual renal function in dialysis patients’ prognoses.  Although the benefits of residual renal function are most obvious in patients undergoing peritoneal…

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How to lose a kidney

Couldn’t figure out how to embed the video so I’ve just posted the link of a daredevil who “exploded his kidney” (according to the video at least) during a bike jump. Just think, somewhere out there there’s a…

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Betel Nut Chewing

Following up on the discussion of milk-alkali syndrome, a similar syndrome (hypercalcemia, metabolic alkalosis, and acute renal failure) may also occur due to betel nut chewing. Betel nut chewing is a common habit and cultural practice amongst Indian…

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History of the Milk-Alkali Syndrome

Heard about a case of milk-alkali syndrome at Renal Grand Rounds yesterday. This is an interesting condition whose pathophysiologic mechanism really tests your knowledge of calcium and acid-base homeostasis. I won’t attempt to chart the pathway but a…

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